Rapid spread of OXA-244-producing Escherichia coli ST38 in Germany: insights from an integrated molecular surveillance approach; 2017 to January 2020

Annually, increasing numbers of OXA-244-producing Escherichia coli in 13 German federal states prompted us to initiate an outbreak investigation. Whole genome sequencing revealed that among 148 isolates analysed, most belonged to sequence type 38 with 62 isolates forming a genetically distinct clust...

Descripción completa

Detalles Bibliográficos
Autores principales: Kremer, Katrin, Kramer, Rolf, Neumann, Bernd, Haller, Sebastian, Pfennigwerth, Niels, Werner, Guido, Gatermann, Sören, Schroten, Horst, Eckmanns, Tim, Hans, Jörg B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2020
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331143/
https://www.ncbi.nlm.nih.gov/pubmed/32613940
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.25.2000923
Descripción
Sumario:Annually, increasing numbers of OXA-244-producing Escherichia coli in 13 German federal states prompted us to initiate an outbreak investigation. Whole genome sequencing revealed that among 148 isolates analysed, most belonged to sequence type 38 with 62 isolates forming a genetically distinct cluster. Although no epidemiological link could be identified between cases, ongoing investigations suggest non-healthcare associated transmission. A screening-PCR was developed facilitating early detection of ST38 cluster isolates to identify the source and transmission route.

Ejemplares similares