Cargando…

Amide Synthesis through the In Situ Generation of Chloro- and Imido-Phosphonium Salts

[Image: see text] We describe a methodology for the amidation of carboxylic acids by generating phosphonium salts in situ from N-chlorophthalimide and triphenylphosphine. Aliphatic, benzylic, and aromatic carboxylic acids can be transformed into their amide counter parts using primary and secondary...

Descripción completa

Detalles Bibliográficos
Autores principales: Irving, Charles D., Floreancig, Jack T., Laulhé, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331200/
https://www.ncbi.nlm.nih.gov/pubmed/32637849
http://dx.doi.org/10.1021/acsomega.0c02309