Angiotensin II receptor 1 antibodies associate with post-transplant focal segmental glomerulosclerosis and proteinuria

BACKGROUND: Angiotensin II type 1 receptors (AT1Rs) are expressed on podocytes, endothelial and other cells, and play an essential role in the maintenance of podocyte function and vascular homeostasis. The presence of AT1R antibodies (AT1R-Abs) leads to activation of these receptors resulting in pod...

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Detalles Bibliográficos
Autores principales: Abuzeineh, Mohammad, Aala, Amtul, Alasfar, Sami, Alachkar, Nada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331243/
https://www.ncbi.nlm.nih.gov/pubmed/32615995
http://dx.doi.org/10.1186/s12882-020-01910-w

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