Cargando…

PODXL might be a new prognostic biomarker in various cancers: a meta-analysis and sequential verification with TCGA datasets

BACKGROUND: Several studies have investigated the associations between the podocalyxin-like protein (PODXL) expression quantity or locations and cancers survival, but the results were far from conclusive. Therefore, we proceeded a meta-analysis on PODXL in various human cancers to find its prognosti...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Siying, Du, Wenjie, Li, Menglan, Yan, Ming, Zheng, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331259/ https://www.ncbi.nlm.nih.gov/pubmed/32615943 http://dx.doi.org/10.1186/s12885-020-07108-5

Ejemplares similares

Prognostic Biomarkers in Pancreatic Cancer: Avoiding Errata When Using the TCGA Dataset
por: Nicolle, Remy, et al.
Publicado: (2019)

Subtype identification from heterogeneous TCGA datasets on a genomic scale by multi-view clustering with enhanced consensus
por: Cai, Menglan, et al.
Publicado: (2017)

Measurement of serum PODXL concentration for detection of pancreatic cancer
por: Taniuchi, Keisuke, et al.
Publicado: (2018)

Expression Differentiation Is Not Helpful in Identifying Prognostic Genes Based on TCGA Datasets
por: An, Ning, et al.
Publicado: (2018)

Prognostic value of miR-21 in gliomas: comprehensive study based on meta-analysis and TCGA dataset validation
por: Jiang, Guli, et al.
Publicado: (2020)

Prognostic Value of HMGA2 in Human Cancers: A Meta-Analysis Based on Literatures and TCGA Datasets
por: Huang, Ben, et al.
Publicado: (2018)

Multifaceted role of RNA editing in promoting loss-of-function of PODXL in cancer
por: Fu, Ting, et al.
Publicado: (2022)

Establishment and verification of a prognostic model of liver cancer by RNA-binding proteins based on the TCGA database
por: Apizi, Anwaier, et al.
Publicado: (2022)

A bioinformatics-to-clinic sequential approach to analysis of prostate cancer biomarkers using TCGA datasets and clinical samples: a new method for precision oncology?
por: Yoshie, Hidekazu, et al.
Publicado: (2017)

TCF3 Regulates the Proliferation and Apoptosis of Human Spermatogonial Stem Cells by Targeting PODXL
por: Zhou, Dai, et al.
Publicado: (2021)

A comparative study of two PODXL antibodies in 840 colorectal cancer patients
por: Kaprio, Tuomas, et al.
Publicado: (2014)

Atypical focal segmental glomerulosclerosis associated with a new PODXL nonsense variant
por: Marx, David, et al.
Publicado: (2021)

PODXL, negatively regulated by KLF4, promotes the EMT and metastasis and serves as a novel prognostic indicator of gastric cancer
por: Zhang, Jing, et al.
Publicado: (2018)

Dead or alive? Pitfall of survival analysis with TCGA datasets
por: Idogawa, Masashi, et al.
Publicado: (2021)

Evaluation of FGFR1 as a diagnostic biomarker for ovarian cancer using TCGA and GEO datasets
por: Xiao, Huiting, et al.
Publicado: (2021)

RNA-binding proteins RBM-HuR, RBM3 and PODXL expression in urothelial carcinoma of the urinary bladder. Prognostic and clinical implications
por: Hafez, Abeer M., et al.
Publicado: (2022)

Identification of a putative competitive endogenous RNA network for lung adenocarcinoma using TCGA datasets
por: Wang, Yuanyong, et al.
Publicado: (2019)

ITGB6-Knockout Suppresses Cholangiocarcinoma Cell Migration and Invasion with Declining PODXL2 Expression
por: Soejima, Yurie, et al.
Publicado: (2021)

Array expression meta-analysis of cancer stem cell genes identifies upregulation of PODXL especially in DCC low expression meningiomas
por: Schulten, Hans-Juergen, et al.
Publicado: (2019)

Analysis of TERT Isoforms across TCGA, GTEx and CCLE Datasets
por: Subasri, Mathushan, et al.
Publicado: (2021)

TCGA and ESTIMATE data mining to identify potential prognostic biomarkers in HCC patients
por: He, Guolin, et al.
Publicado: (2020)

Identification of potential diagnostic and prognostic biomarkers for LUAD based on TCGA and GEO databases
por: Zheng, Qiangqiang, et al.
Publicado: (2021)

Network analysis of TCGA and GTEx gene expression datasets for identification of trait-associated biomarkers in human cancer
por: Chen, Huey-Miin, et al.
Publicado: (2022)

Two miRNA prognostic signatures of head and neck squamous cell carcinoma: A bioinformatic analysis based on the TCGA dataset
por: Wu, Chaoying, et al.
Publicado: (2020)

The clinical prognostic value of lncRNA FOXP4-AS1 in cancer patients: A meta-analysis and bioinformatics analysis based on TCGA datasets
por: Shu, Qiang, et al.
Publicado: (2022)

HOTAIR as a diagnostic and prognostic biomarker of gastrointestinal cancers: an updated meta-analysis and bioinformatics analysis based on TCGA data
por: Yang, Jinyou, et al.
Publicado: (2023)

Biomarkers that might improve prognostic accuracy in ICU patients
por: Karvouniaris, M, et al.
Publicado: (2008)

Identification of Potential Diagnostic and Prognostic Biomarkers for Colorectal Cancer Based on GEO and TCGA Databases
por: Wang, Zhenjiang, et al.
Publicado: (2021)

Exploring novel independent prognostic biomarkers for hepatocellular carcinoma based on TCGA and GEO databases
por: Hou, Miaomiao
Publicado: (2022)

Identification of Druggable Cancer Driver Genes Amplified across TCGA Datasets
por: Chen, Ying, et al.
Publicado: (2014)

Characterization of bidirectional gene pairs in The Cancer Genome Atlas (TCGA) dataset
por: Tu, Juchuanli, et al.
Publicado: (2019)

Long noncoding RNA HOXD-AS1 in various cancers: a meta-analysis and TCGA data review
por: Zhang, Fuhong, et al.
Publicado: (2018)

Prognostic Analysis and Biomarkers Identification of Immune Infiltration in Early and Late Stage Hepatocellular Carcinoma Based on TCGA Data
por: Jiang, Wenying, et al.
Publicado: (2023)

miR-509-3-5P inhibits the invasion and lymphatic metastasis by targeting PODXL and serves as a novel prognostic indicator for gastric cancer
por: Zhang, Jing, et al.
Publicado: (2017)

PODXL2 maintains cellular stemness and promotes breast cancer development through the Rac1/Akt pathway
por: Lin, Yi-Yi, et al.
Publicado: (2020)

Radiation-Induced Overexpression of TGFβ and PODXL Contributes to Colorectal Cancer Cell Radioresistance through Enhanced Motility
por: Lee, Hyunjung, et al.
Publicado: (2021)

Exploration of prognostic biomarkers in head and neck squamous cell carcinoma microenvironment from TCGA database
por: Li, Ying, et al.
Publicado: (2023)

Correction: Identification of Druggable Cancer Driver Genes Amplified across TCGA Datasets
Publicado: (2014)

Identification of Prognosis Associated microRNAs in HNSCC Subtypes Based on TCGA Dataset
por: Chamorro Petronacci, Cintia M., et al.
Publicado: (2020)

Prognostic value of the TCGA molecular classification in uterine carcinosarcoma
por: Travaglino, Antonio, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_96gclcthhghbvg82gsf0mmdjse