Epidemiology and treatment of beta thalassemia major in China

Thalassemia, classified as the main types α‐ and β‐thalassemia, is a single gene disorder resulting from globin chain synthesis impairment through the mutation or deletion of globin genes. The incidence of thalassemia is high worldwide, with high associated mortality. Therefore, treatment is importa...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Xiaoxiao, Wu, Xuedong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331292/
https://www.ncbi.nlm.nih.gov/pubmed/32851341
http://dx.doi.org/10.1002/ped4.12154
_version_ 1783553296393306112
author Xu, Xiaoxiao
Wu, Xuedong
author_facet Xu, Xiaoxiao
Wu, Xuedong
author_sort Xu, Xiaoxiao
collection PubMed
description Thalassemia, classified as the main types α‐ and β‐thalassemia, is a single gene disorder resulting from globin chain synthesis impairment through the mutation or deletion of globin genes. The incidence of thalassemia is high worldwide, with high associated mortality. Therefore, treatment is important to improve patient outcomes. This paper reviews the current status of β‐thalassemia major in China, including its epidemiology and treatment.
format Online
Article
Text
id pubmed-7331292
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-73312922020-08-25 Epidemiology and treatment of beta thalassemia major in China Xu, Xiaoxiao Wu, Xuedong Pediatr Investig Review Thalassemia, classified as the main types α‐ and β‐thalassemia, is a single gene disorder resulting from globin chain synthesis impairment through the mutation or deletion of globin genes. The incidence of thalassemia is high worldwide, with high associated mortality. Therefore, treatment is important to improve patient outcomes. This paper reviews the current status of β‐thalassemia major in China, including its epidemiology and treatment. John Wiley and Sons Inc. 2019-10-28 /pmc/articles/PMC7331292/ /pubmed/32851341 http://dx.doi.org/10.1002/ped4.12154 Text en © 2019 Chinese Medical Association. Pediatric Investigation published by John Wiley & Sons Australia, Ltd on behalf of Futang Research Center of Pediatric Development This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Review
Xu, Xiaoxiao
Wu, Xuedong
Epidemiology and treatment of beta thalassemia major in China
title Epidemiology and treatment of beta thalassemia major in China
title_full Epidemiology and treatment of beta thalassemia major in China
title_fullStr Epidemiology and treatment of beta thalassemia major in China
title_full_unstemmed Epidemiology and treatment of beta thalassemia major in China
title_short Epidemiology and treatment of beta thalassemia major in China
title_sort epidemiology and treatment of beta thalassemia major in china
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331292/
https://www.ncbi.nlm.nih.gov/pubmed/32851341
http://dx.doi.org/10.1002/ped4.12154
work_keys_str_mv AT xuxiaoxiao epidemiologyandtreatmentofbetathalassemiamajorinchina
AT wuxuedong epidemiologyandtreatmentofbetathalassemiamajorinchina

Ejemplares similares