Clinical research study designs: The essentials

In clinical research, our aim is to design a study which would be able to derive a valid and meaningful scientific conclusion using appropriate statistical methods. The conclusions derived from a research study can either improve health care or result in inadvertent harm to patients. Hence, this req...

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Detalles Bibliográficos
Autores principales: Chidambaram, Ambika G., Josephson, Maureen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Lecture
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331444/
https://www.ncbi.nlm.nih.gov/pubmed/32851330
http://dx.doi.org/10.1002/ped4.12166
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author Chidambaram, Ambika G.
Josephson, Maureen
author_facet Chidambaram, Ambika G.
Josephson, Maureen
author_sort Chidambaram, Ambika G.
collection PubMed
description In clinical research, our aim is to design a study which would be able to derive a valid and meaningful scientific conclusion using appropriate statistical methods. The conclusions derived from a research study can either improve health care or result in inadvertent harm to patients. Hence, this requires a well‐designed clinical research study that rests on a strong foundation of a detailed methodology and governed by ethical clinical principles. The purpose of this review is to provide the readers an overview of the basic study designs and its applicability in clinical research.
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spelling pubmed-73314442020-08-25 Clinical research study designs: The essentials Chidambaram, Ambika G. Josephson, Maureen Pediatr Investig Lecture In clinical research, our aim is to design a study which would be able to derive a valid and meaningful scientific conclusion using appropriate statistical methods. The conclusions derived from a research study can either improve health care or result in inadvertent harm to patients. Hence, this requires a well‐designed clinical research study that rests on a strong foundation of a detailed methodology and governed by ethical clinical principles. The purpose of this review is to provide the readers an overview of the basic study designs and its applicability in clinical research. John Wiley and Sons Inc. 2019-12-21 /pmc/articles/PMC7331444/ /pubmed/32851330 http://dx.doi.org/10.1002/ped4.12166 Text en © 2019 Chinese Medical Association. Pediatric Investigation published by John Wiley & Sons Australia, Ltd on behalf of Futang Research Center of Pediatric Development. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Lecture
Chidambaram, Ambika G.
Josephson, Maureen
Clinical research study designs: The essentials
title Clinical research study designs: The essentials
title_full Clinical research study designs: The essentials
title_fullStr Clinical research study designs: The essentials
title_full_unstemmed Clinical research study designs: The essentials
title_short Clinical research study designs: The essentials
title_sort clinical research study designs: the essentials
topic Lecture
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331444/
https://www.ncbi.nlm.nih.gov/pubmed/32851330
http://dx.doi.org/10.1002/ped4.12166
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