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Successful treatment of a female pediatric patient with carbamazepine‐induced toxic epidermal necrolysis: Active wound care and systemic therapy

We describe a 6‐year‐old female patient who developed carbamazepine‐associated toxic epidermal necrolysis. With active wound care, systemic methylprednisolone and intravenous immunoglobulin pulse therapies and multidisciplinary supportive care, the patient improved significantly. This case indicates...

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Detalles Bibliográficos
Autores principales: Liang, Yuan, Chu, Yan, Xu, Zigang, Ma, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331447/
https://www.ncbi.nlm.nih.gov/pubmed/32851244
http://dx.doi.org/10.1002/ped4.12040
Descripción
Sumario:We describe a 6‐year‐old female patient who developed carbamazepine‐associated toxic epidermal necrolysis. With active wound care, systemic methylprednisolone and intravenous immunoglobulin pulse therapies and multidisciplinary supportive care, the patient improved significantly. This case indicates that improving the management of Stevens‐Johnson syndrome/Toxic epidermal necrolysis patients requires attention not only to the process of wound management but also to individual supportive care and active therapeutic intervention. Only through this can standardized care, including muco‐cutaneous and visceral wound care, be delivered to provide high‐quality care with improved clinical prognosis and quality of life.