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Successful treatment of a female pediatric patient with carbamazepine‐induced toxic epidermal necrolysis: Active wound care and systemic therapy

We describe a 6‐year‐old female patient who developed carbamazepine‐associated toxic epidermal necrolysis. With active wound care, systemic methylprednisolone and intravenous immunoglobulin pulse therapies and multidisciplinary supportive care, the patient improved significantly. This case indicates...

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Detalles Bibliográficos
Autores principales: Liang, Yuan, Chu, Yan, Xu, Zigang, Ma, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331447/
https://www.ncbi.nlm.nih.gov/pubmed/32851244
http://dx.doi.org/10.1002/ped4.12040
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author Liang, Yuan
Chu, Yan
Xu, Zigang
Ma, Lin
author_facet Liang, Yuan
Chu, Yan
Xu, Zigang
Ma, Lin
author_sort Liang, Yuan
collection PubMed
description We describe a 6‐year‐old female patient who developed carbamazepine‐associated toxic epidermal necrolysis. With active wound care, systemic methylprednisolone and intravenous immunoglobulin pulse therapies and multidisciplinary supportive care, the patient improved significantly. This case indicates that improving the management of Stevens‐Johnson syndrome/Toxic epidermal necrolysis patients requires attention not only to the process of wound management but also to individual supportive care and active therapeutic intervention. Only through this can standardized care, including muco‐cutaneous and visceral wound care, be delivered to provide high‐quality care with improved clinical prognosis and quality of life.
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spelling pubmed-73314472020-08-25 Successful treatment of a female pediatric patient with carbamazepine‐induced toxic epidermal necrolysis: Active wound care and systemic therapy Liang, Yuan Chu, Yan Xu, Zigang Ma, Lin Pediatr Investig Clinical Experience We describe a 6‐year‐old female patient who developed carbamazepine‐associated toxic epidermal necrolysis. With active wound care, systemic methylprednisolone and intravenous immunoglobulin pulse therapies and multidisciplinary supportive care, the patient improved significantly. This case indicates that improving the management of Stevens‐Johnson syndrome/Toxic epidermal necrolysis patients requires attention not only to the process of wound management but also to individual supportive care and active therapeutic intervention. Only through this can standardized care, including muco‐cutaneous and visceral wound care, be delivered to provide high‐quality care with improved clinical prognosis and quality of life. John Wiley and Sons Inc. 2018-07-16 /pmc/articles/PMC7331447/ /pubmed/32851244 http://dx.doi.org/10.1002/ped4.12040 Text en © 2018 Chinese Medical Association. Pediatric Investigation published by John Wiley & Sons Australia, Ltd on behalf of Futang Research Center of Pediatric Development This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Clinical Experience
Liang, Yuan
Chu, Yan
Xu, Zigang
Ma, Lin
Successful treatment of a female pediatric patient with carbamazepine‐induced toxic epidermal necrolysis: Active wound care and systemic therapy
title Successful treatment of a female pediatric patient with carbamazepine‐induced toxic epidermal necrolysis: Active wound care and systemic therapy
title_full Successful treatment of a female pediatric patient with carbamazepine‐induced toxic epidermal necrolysis: Active wound care and systemic therapy
title_fullStr Successful treatment of a female pediatric patient with carbamazepine‐induced toxic epidermal necrolysis: Active wound care and systemic therapy
title_full_unstemmed Successful treatment of a female pediatric patient with carbamazepine‐induced toxic epidermal necrolysis: Active wound care and systemic therapy
title_short Successful treatment of a female pediatric patient with carbamazepine‐induced toxic epidermal necrolysis: Active wound care and systemic therapy
title_sort successful treatment of a female pediatric patient with carbamazepine‐induced toxic epidermal necrolysis: active wound care and systemic therapy
topic Clinical Experience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331447/
https://www.ncbi.nlm.nih.gov/pubmed/32851244
http://dx.doi.org/10.1002/ped4.12040
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