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Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report

Although invasive pulmonary aspergillosis (IPA) is typically described in immunocompromised host, patient with severe influenzae can develop IPA. Similarly, patients with severe COVID-19 complicated with IPA are increasingly reported. Here, we describe a case of invasive aspergillosis with triazole-...

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Autores principales: Ghelfenstein-Ferreira, Théo, Saade, Anastasia, Alanio, Alexandre, Bretagne, Stéphane, Araujo de Castro, Raffael, Hamane, Samia, Azoulay, Elie, Bredin, Swann, Dellière, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331532/
https://www.ncbi.nlm.nih.gov/pubmed/32837880
http://dx.doi.org/10.1016/j.mmcr.2020.06.006
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author Ghelfenstein-Ferreira, Théo
Saade, Anastasia
Alanio, Alexandre
Bretagne, Stéphane
Araujo de Castro, Raffael
Hamane, Samia
Azoulay, Elie
Bredin, Swann
Dellière, Sarah
author_facet Ghelfenstein-Ferreira, Théo
Saade, Anastasia
Alanio, Alexandre
Bretagne, Stéphane
Araujo de Castro, Raffael
Hamane, Samia
Azoulay, Elie
Bredin, Swann
Dellière, Sarah
author_sort Ghelfenstein-Ferreira, Théo
collection PubMed
description Although invasive pulmonary aspergillosis (IPA) is typically described in immunocompromised host, patient with severe influenzae can develop IPA. Similarly, patients with severe COVID-19 complicated with IPA are increasingly reported. Here, we describe a case of invasive aspergillosis with triazole-resistant A. fumigatus (TR34/L98H mutation) in a 56-year-old patient with COVID-19 in intensive care unit. This report highlights the need to define the available tools for diagnosis of invasive aspergillosis in severe COVID-19 patients.
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spelling pubmed-73315322020-07-06 Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report Ghelfenstein-Ferreira, Théo Saade, Anastasia Alanio, Alexandre Bretagne, Stéphane Araujo de Castro, Raffael Hamane, Samia Azoulay, Elie Bredin, Swann Dellière, Sarah Med Mycol Case Rep CAPA Case Report Although invasive pulmonary aspergillosis (IPA) is typically described in immunocompromised host, patient with severe influenzae can develop IPA. Similarly, patients with severe COVID-19 complicated with IPA are increasingly reported. Here, we describe a case of invasive aspergillosis with triazole-resistant A. fumigatus (TR34/L98H mutation) in a 56-year-old patient with COVID-19 in intensive care unit. This report highlights the need to define the available tools for diagnosis of invasive aspergillosis in severe COVID-19 patients. Elsevier 2020-07-02 /pmc/articles/PMC7331532/ /pubmed/32837880 http://dx.doi.org/10.1016/j.mmcr.2020.06.006 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle CAPA Case Report
Ghelfenstein-Ferreira, Théo
Saade, Anastasia
Alanio, Alexandre
Bretagne, Stéphane
Araujo de Castro, Raffael
Hamane, Samia
Azoulay, Elie
Bredin, Swann
Dellière, Sarah
Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report
title Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report
title_full Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report
title_fullStr Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report
title_full_unstemmed Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report
title_short Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report
title_sort recovery of a triazole-resistant aspergillus fumigatus in respiratory specimen of covid-19 patient in icu – a case report
topic CAPA Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331532/
https://www.ncbi.nlm.nih.gov/pubmed/32837880
http://dx.doi.org/10.1016/j.mmcr.2020.06.006
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