Acute Cellular and Functional Changes With a Combinatorial Treatment of Ion Channel Inhibitors Following Spinal Cord Injury

Reducing the extent of secondary degeneration following spinal cord injury (SCI) is necessary to preserve function, but treatment options have thus far been limited. A combination of the ion channel inhibitors Lomerizine (Lom), YM872 and oxATP, to inhibit voltage-gated Ca(2+) channels, Ca(2+) permea...

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Detalles Bibliográficos
Autores principales: O’Hare Doig, Ryan L., Santhakumar, Sreya, Fehily, Brooke, Raja, Sushmitha, Solomon, Tanya, Bartlett, Carole A., Fitzgerald, Melinda, Hodgetts, Stuart I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331598/
https://www.ncbi.nlm.nih.gov/pubmed/32670018
http://dx.doi.org/10.3389/fnmol.2020.00085

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