Cyclophilin inhibitors restrict Middle East respiratory syndrome coronavirus via interferon-λ in vitro and in mice

While severe coronavirus infections, including Middle East respiratory syndrome coronavirus (MERS-CoV), cause lung injury with high mortality rates, protective treatment strategies are not approved for clinical use. We elucidated the molecular mechanisms by which the cyclophilin inhibitors cyclospor...

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Detalles Bibliográficos
Autores principales: Sauerhering, Lucie, Kupke, Alexandra, Meier, Lars, Dietzel, Erik, Hoppe, Judith, Gruber, Achim D., Gattenloehner, Stefan, Witte, Biruta, Fink, Ludger, Hofmann, Nina, Zimmermann, Tobias, Goesmann, Alexander, Nist, Andrea, Stiewe, Thorsten, Becker, Stephan, Herold, Susanne, Peteranderl, Christin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331652/
https://www.ncbi.nlm.nih.gov/pubmed/32616594
http://dx.doi.org/10.1183/13993003.01826-2019

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