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Somatic copy number profiling from hepatocellular carcinoma circulating tumor cells

Somatic copy number alterations (SCNAs) are important genetic drivers of many cancers. We investigated the feasibility of obtaining SCNA profiles from circulating tumor cells (CTCs) as a molecular liquid biopsy for hepatocellular carcinoma (HCC). CTCs from ten HCC patients underwent SCNA profiling....

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Detalles Bibliográficos
Autores principales: Court, Colin M., Hou, Shuang, Liu, Lian, Winograd, Paul, DiPardo, Benjamin J., Liu, Sean X., Chen, Pin-Jung, Zhu, Yazhen, Smalley, Matthew, Zhang, Ryan, Sadeghi, Saeed, Finn, Richard S., Kaldas, Fady M., Busuttil, Ronald W., Zhou, Xianghong J., Tseng, Hsian-Rong, Tomlinson, James S., Graeber, Thomas G., Agopian, Vatche G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331695/
https://www.ncbi.nlm.nih.gov/pubmed/32637655
http://dx.doi.org/10.1038/s41698-020-0123-0

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