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Repression of tick microRNA-133 induces organic anion transporting polypeptide expression critical for Anaplasma phagocytophilum survival in the vector and transmission to the vertebrate host

The microRNAs (miRNAs) are important regulators of gene expression. In this study, we provide evidence for the first time to show that rickettsial pathogen Anaplasma phagocytophilum infection results in the down-regulation of tick microRNA-133 (miR-133), to induce Ixodes scapularis organic anion tra...

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Detalles Bibliográficos
Autores principales: Ramasamy, Ellango, Taank, Vikas, Anderson, John F, Sultana, Hameeda, Neelakanta, Girish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331985/
https://www.ncbi.nlm.nih.gov/pubmed/32614824
http://dx.doi.org/10.1371/journal.pgen.1008856