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Disruption of Osteoprotegerin has complex effects on medial destruction and adventitial fibrosis during mouse abdominal aortic aneurysm formation
Aortic aneurysm refers to dilatation of the aorta due to loss of elasticity and degenerative weakening of its wall. A preventive role for osteoprotegerin (Opg) in the development of abdominal aortic aneurysm has been reported in the CaCl(2)-induced aneurysm model, whereas Opg was found to promote su...
Autores principales: | Bumdelger, Batmunkh, Otani, Mikage, Karasaki, Kohei, Sakai, Chiemi, Ishida, Mari, Kokubo, Hiroki, Yoshizumi, Masao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331998/ https://www.ncbi.nlm.nih.gov/pubmed/32614927 http://dx.doi.org/10.1371/journal.pone.0235553 |
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