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Activation of MAPK and Cyclin D1/CDK4 in Malignant Transformation of Human Embryonic Lung Fibroblasts Induced by Silica and Benzopyrene

OBJECTIVE: Silica and Benzo(a)pyrene are listed as carcinogens. This study aims to explore Cyclin D1, CDK4 and difference of cell cycle adjusted by MAPK signal transduction pathway in silica and B(a)P-induced malignant transformation of human embryonic lung fibroblasts. METHODS: Activity of the subf...

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Detalles Bibliográficos
Autores principales:	Wang, Huan, Xiao, Shuyu, Tang, Yali, Han, Ke, Zhang, Zheng, Jin, Yulan, Shen, Fuhai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332116/ https://www.ncbi.nlm.nih.gov/pubmed/32102502 http://dx.doi.org/10.31557/APJCP.2020.21.2.295

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