LncRNAs as Potential Therapeutic Targets in Thyroid Cancer

Thyroid cancer (TC) is the most common cancer of endocrine system. TC can be subdivided into 4 different entities, papillary, follicular, medullary and anaplastic thyroid cancer. Among them, anaplastic thyroid cancer has the poorest prognosis. Exploring new therapeutic approach may entail favorable...

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Autores principales: Javed, Zeeshan, Shah, Faiez Ahmed, Rajabi, Sadegh, Raza, Qamar, Iqbal, Zaheer, Ullah, Mukhtar, Ahmad, Touqeer, Salehi, Bahare, Sharifi-Rad, Mehdi, Pezzani, Raffaele, Yaqoob, Farooq, Sadia, Haleema, Iriti, Marcello, Sharifi-Rad, Javad, Cho, William C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332117/
https://www.ncbi.nlm.nih.gov/pubmed/32102500
http://dx.doi.org/10.31557/APJCP.2020.21.2.281
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author Javed, Zeeshan
Shah, Faiez Ahmed
Rajabi, Sadegh
Raza, Qamar
Iqbal, Zaheer
Ullah, Mukhtar
Ahmad, Touqeer
Salehi, Bahare
Sharifi-Rad, Mehdi
Pezzani, Raffaele
Yaqoob, Farooq
Sadia, Haleema
Iriti, Marcello
Sharifi-Rad, Javad
Cho, William C
author_facet Javed, Zeeshan
Shah, Faiez Ahmed
Rajabi, Sadegh
Raza, Qamar
Iqbal, Zaheer
Ullah, Mukhtar
Ahmad, Touqeer
Salehi, Bahare
Sharifi-Rad, Mehdi
Pezzani, Raffaele
Yaqoob, Farooq
Sadia, Haleema
Iriti, Marcello
Sharifi-Rad, Javad
Cho, William C
author_sort Javed, Zeeshan
collection PubMed
description Thyroid cancer (TC) is the most common cancer of endocrine system. TC can be subdivided into 4 different entities, papillary, follicular, medullary and anaplastic thyroid cancer. Among them, anaplastic thyroid cancer has the poorest prognosis. Exploring new therapeutic approach may entail favorable prediction as well as increasing overall survival rate of patients. Long non-coding RNAs (lncRNAs), have vast implications in different cancer types. Although they are not transcribed into proteins, they can act as a harness in regulating a plethora of biological functions. They have been implicated in a decisive role in gene expression via modulation of both coding and non-coding RNAs. This article discuss the multi-facet role of lncRNA in thyroid cancer biology.
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spelling pubmed-73321172020-07-07 LncRNAs as Potential Therapeutic Targets in Thyroid Cancer Javed, Zeeshan Shah, Faiez Ahmed Rajabi, Sadegh Raza, Qamar Iqbal, Zaheer Ullah, Mukhtar Ahmad, Touqeer Salehi, Bahare Sharifi-Rad, Mehdi Pezzani, Raffaele Yaqoob, Farooq Sadia, Haleema Iriti, Marcello Sharifi-Rad, Javad Cho, William C Asian Pac J Cancer Prev Review Article Thyroid cancer (TC) is the most common cancer of endocrine system. TC can be subdivided into 4 different entities, papillary, follicular, medullary and anaplastic thyroid cancer. Among them, anaplastic thyroid cancer has the poorest prognosis. Exploring new therapeutic approach may entail favorable prediction as well as increasing overall survival rate of patients. Long non-coding RNAs (lncRNAs), have vast implications in different cancer types. Although they are not transcribed into proteins, they can act as a harness in regulating a plethora of biological functions. They have been implicated in a decisive role in gene expression via modulation of both coding and non-coding RNAs. This article discuss the multi-facet role of lncRNA in thyroid cancer biology. West Asia Organization for Cancer Prevention 2020 /pmc/articles/PMC7332117/ /pubmed/32102500 http://dx.doi.org/10.31557/APJCP.2020.21.2.281 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Javed, Zeeshan
Shah, Faiez Ahmed
Rajabi, Sadegh
Raza, Qamar
Iqbal, Zaheer
Ullah, Mukhtar
Ahmad, Touqeer
Salehi, Bahare
Sharifi-Rad, Mehdi
Pezzani, Raffaele
Yaqoob, Farooq
Sadia, Haleema
Iriti, Marcello
Sharifi-Rad, Javad
Cho, William C
LncRNAs as Potential Therapeutic Targets in Thyroid Cancer
title LncRNAs as Potential Therapeutic Targets in Thyroid Cancer
title_full LncRNAs as Potential Therapeutic Targets in Thyroid Cancer
title_fullStr LncRNAs as Potential Therapeutic Targets in Thyroid Cancer
title_full_unstemmed LncRNAs as Potential Therapeutic Targets in Thyroid Cancer
title_short LncRNAs as Potential Therapeutic Targets in Thyroid Cancer
title_sort lncrnas as potential therapeutic targets in thyroid cancer
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332117/
https://www.ncbi.nlm.nih.gov/pubmed/32102500
http://dx.doi.org/10.31557/APJCP.2020.21.2.281
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