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p53, Cyclin-D1, β-catenin, APC and c-myc in Tumor Tissue from Colorectal and Gastric Cancer Patients with Suspected Lynch Syndrome by the Bethesda Criteria

Colorectal cancer (CRC) is one of the most frequent neoplasms worldwide, and up to 15% have a family history. Lynch syndrome (LS) is a hereditary cause of CRC and gastric (GC). Individuals with LS have mutations in mismatch genes repair. p53, cyclin D1, β-catenin, APC and c-myc proteins are involved...

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Detalles Bibliográficos
Autores principales: Marcolino, Tais Fernanda, Pimenta, Celia Aparecida Marques, Neto, Ricardo Artigiani, Castelo, Paula, Silva, Marcelo Souza, Forones, Nora Manoukian, Oshima, Celina Tizuko Fujiyama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332149/
https://www.ncbi.nlm.nih.gov/pubmed/32102509
http://dx.doi.org/10.31557/APJCP.2020.21.2.343

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