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Particle therapy in Europe

Particle therapy using protons or heavier ions is currently the most advanced form of radiotherapy and offers new opportunities for improving cancer care and research. Ions deposit the dose with a sharp maximum – the Bragg peak – and normal tissue receives a much lower dose than what is delivered by...

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Autores principales: Grau, Cai, Durante, Marco, Georg, Dietmar, Langendijk, Johannes A., Weber, Damien C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332216/
https://www.ncbi.nlm.nih.gov/pubmed/32223048
http://dx.doi.org/10.1002/1878-0261.12677
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author Grau, Cai
Durante, Marco
Georg, Dietmar
Langendijk, Johannes A.
Weber, Damien C.
author_facet Grau, Cai
Durante, Marco
Georg, Dietmar
Langendijk, Johannes A.
Weber, Damien C.
author_sort Grau, Cai
collection PubMed
description Particle therapy using protons or heavier ions is currently the most advanced form of radiotherapy and offers new opportunities for improving cancer care and research. Ions deposit the dose with a sharp maximum – the Bragg peak – and normal tissue receives a much lower dose than what is delivered by X‐ray therapy. Particle therapy has also biological advantages due to the high linear energy transfer of the charged particles around the Bragg peak. The introduction of particle therapy has been slow in Europe, but within the last decade, more than 20 clinical facilities have opened and facilitated access to this frontline therapy. In this review article, the basic concepts of particle therapy are reviewed along with a presentation of the current clinical indications, the European clinical research, and the established networks.
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spelling pubmed-73322162020-07-07 Particle therapy in Europe Grau, Cai Durante, Marco Georg, Dietmar Langendijk, Johannes A. Weber, Damien C. Mol Oncol Reviews Particle therapy using protons or heavier ions is currently the most advanced form of radiotherapy and offers new opportunities for improving cancer care and research. Ions deposit the dose with a sharp maximum – the Bragg peak – and normal tissue receives a much lower dose than what is delivered by X‐ray therapy. Particle therapy has also biological advantages due to the high linear energy transfer of the charged particles around the Bragg peak. The introduction of particle therapy has been slow in Europe, but within the last decade, more than 20 clinical facilities have opened and facilitated access to this frontline therapy. In this review article, the basic concepts of particle therapy are reviewed along with a presentation of the current clinical indications, the European clinical research, and the established networks. John Wiley and Sons Inc. 2020-04-22 2020-07 /pmc/articles/PMC7332216/ /pubmed/32223048 http://dx.doi.org/10.1002/1878-0261.12677 Text en © 2020 The Authors. Published by FEBS Press and John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Grau, Cai
Durante, Marco
Georg, Dietmar
Langendijk, Johannes A.
Weber, Damien C.
Particle therapy in Europe
title Particle therapy in Europe
title_full Particle therapy in Europe
title_fullStr Particle therapy in Europe
title_full_unstemmed Particle therapy in Europe
title_short Particle therapy in Europe
title_sort particle therapy in europe
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332216/
https://www.ncbi.nlm.nih.gov/pubmed/32223048
http://dx.doi.org/10.1002/1878-0261.12677
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