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Particle therapy in Europe
Particle therapy using protons or heavier ions is currently the most advanced form of radiotherapy and offers new opportunities for improving cancer care and research. Ions deposit the dose with a sharp maximum – the Bragg peak – and normal tissue receives a much lower dose than what is delivered by...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332216/ https://www.ncbi.nlm.nih.gov/pubmed/32223048 http://dx.doi.org/10.1002/1878-0261.12677 |
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author | Grau, Cai Durante, Marco Georg, Dietmar Langendijk, Johannes A. Weber, Damien C. |
author_facet | Grau, Cai Durante, Marco Georg, Dietmar Langendijk, Johannes A. Weber, Damien C. |
author_sort | Grau, Cai |
collection | PubMed |
description | Particle therapy using protons or heavier ions is currently the most advanced form of radiotherapy and offers new opportunities for improving cancer care and research. Ions deposit the dose with a sharp maximum – the Bragg peak – and normal tissue receives a much lower dose than what is delivered by X‐ray therapy. Particle therapy has also biological advantages due to the high linear energy transfer of the charged particles around the Bragg peak. The introduction of particle therapy has been slow in Europe, but within the last decade, more than 20 clinical facilities have opened and facilitated access to this frontline therapy. In this review article, the basic concepts of particle therapy are reviewed along with a presentation of the current clinical indications, the European clinical research, and the established networks. |
format | Online Article Text |
id | pubmed-7332216 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73322162020-07-07 Particle therapy in Europe Grau, Cai Durante, Marco Georg, Dietmar Langendijk, Johannes A. Weber, Damien C. Mol Oncol Reviews Particle therapy using protons or heavier ions is currently the most advanced form of radiotherapy and offers new opportunities for improving cancer care and research. Ions deposit the dose with a sharp maximum – the Bragg peak – and normal tissue receives a much lower dose than what is delivered by X‐ray therapy. Particle therapy has also biological advantages due to the high linear energy transfer of the charged particles around the Bragg peak. The introduction of particle therapy has been slow in Europe, but within the last decade, more than 20 clinical facilities have opened and facilitated access to this frontline therapy. In this review article, the basic concepts of particle therapy are reviewed along with a presentation of the current clinical indications, the European clinical research, and the established networks. John Wiley and Sons Inc. 2020-04-22 2020-07 /pmc/articles/PMC7332216/ /pubmed/32223048 http://dx.doi.org/10.1002/1878-0261.12677 Text en © 2020 The Authors. Published by FEBS Press and John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Grau, Cai Durante, Marco Georg, Dietmar Langendijk, Johannes A. Weber, Damien C. Particle therapy in Europe |
title | Particle therapy in Europe |
title_full | Particle therapy in Europe |
title_fullStr | Particle therapy in Europe |
title_full_unstemmed | Particle therapy in Europe |
title_short | Particle therapy in Europe |
title_sort | particle therapy in europe |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332216/ https://www.ncbi.nlm.nih.gov/pubmed/32223048 http://dx.doi.org/10.1002/1878-0261.12677 |
work_keys_str_mv | AT graucai particletherapyineurope AT durantemarco particletherapyineurope AT georgdietmar particletherapyineurope AT langendijkjohannesa particletherapyineurope AT weberdamienc particletherapyineurope |