Cargando…

Genome-Wide Analysis Identifies NURR1-Controlled Network of New Synapse Formation and Cell Cycle Arrest in Human Neural Stem Cells

Nuclear receptor-related 1 (Nurr1) protein has been identified as an obligatory transcription factor in midbrain dopaminergic neurogenesis, but the global set of human NURR1 target genes remains unexplored. Here, we identified direct gene targets of NURR1 by analyzing genome-wide differential expres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Soo Min, Cho, Soo Young, Kim, Min Woong, Roh, Seung Ryul, Shin, Hee Sun, Suh, Young Ho, Geum, Dongho, Lee, Myung Ae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332357/ https://www.ncbi.nlm.nih.gov/pubmed/32522891 http://dx.doi.org/10.14348/molcells.2020.0071

Ejemplares similares

Nurr1 Represses Tyrosine Hydroxylase Expression via SIRT1 in Human Neural Stem Cells
por: Kim, Tae Eun, et al.
Publicado: (2013)

Pharmacological Stimulation of Nurr1 Promotes Cell Cycle Progression in Adult Hippocampal Neural Stem Cells
por: Moon, Haena, et al.
Publicado: (2019)

Propionate of a microbiota metabolite induces cell apoptosis and cell cycle arrest in lung cancer
por: Kim, Kwangkho, et al.
Publicado: (2019)

Potent synthetic and endogenous ligands for the adopted orphan nuclear receptor Nurr1
por: Jang, Yongwoo, et al.
Publicado: (2021)

An optimized Nurr1 agonist provides disease-modifying effects in Parkinson’s disease models
por: Kim, Woori, et al.
Publicado: (2023)

EHMT1 knockdown induces apoptosis and cell cycle arrest in lung cancer cells by increasing CDKN1A expression
por: Lee, Jinkwon, et al.
Publicado: (2021)

Chloroquine modulates inflammatory autoimmune responses through Nurr1 in autoimmune diseases
por: Park, Tae-Yoon, et al.
Publicado: (2019)

Inhibition of MUC1 exerts cell-cycle arrest and telomerase suppression in glioblastoma cells
por: Kim, Sojin, et al.
Publicado: (2020)

Inositol Pyrophosphate Metabolism Regulates Presynaptic Vesicle Cycling at Central Synapses
por: Park, Seung Ju, et al.
Publicado: (2020)

Induction of p53-Independent Apoptosis and G1 Cell Cycle Arrest by Fucoidan in HCT116 Human Colorectal Carcinoma Cells
por: Park, Hye Young, et al.
Publicado: (2017)

Quantitative Immunohistochemistry to Measure Regional Expression of Nurr1 in the Brain and the Effect of the Nurr1 Heterozygous Genotype
por: Kummari, Evangel, et al.
Publicado: (2021)

α-Mangostin Induces Apoptosis and Cell Cycle Arrest in Oral Squamous Cell Carcinoma Cell
por: Kwak, Hyun-Ho, et al.
Publicado: (2016)

Synchronized Cell Cycle Arrest Promotes Osteoclast Differentiation
por: Kwon, Minsuk, et al.
Publicado: (2016)

NURR1 Impairment in Multiple Sclerosis
por: Montarolo, Francesca, et al.
Publicado: (2019)

Integrative analysis reveals structural basis for transcription activation of Nurr1 and Nurr1-RXRα heterodimer
por: Zhao, Mohan, et al.
Publicado: (2022)

Coix lacryma-jobi var. ma-yuen Stapf sprout extract induces cell cycle arrest and apoptosis in human cervical carcinoma cells
por: Son, Eun Suk, et al.
Publicado: (2019)

Nurr1 performs its anti-inflammatory function by regulating RasGRP1 expression in neuro-inflammation
por: Oh, Mihee, et al.
Publicado: (2020)

Synapses in neurodegenerative diseases
por: Bae, Jae Ryul, et al.
Publicado: (2017)

Generation of Dopamine Neurons with Improved Cell Survival and Phenotype Maintenance Using a Degradation-Resistant Nurr1 Mutant
por: Jo, A-Young, et al.
Publicado: (2009)

Extended stability of cyclin D1 contributes to limited cell cycle arrest at G1-phase in BHK-21 cells with Japanese encephalitis virus persistent infection
por: Kim, Ji Young, et al.
Publicado: (2015)

Hwanggeumchal sorghum Induces Cell Cycle Arrest, and Suppresses Tumor Growth and Metastasis through Jak2/STAT Pathways in Breast Cancer Xenografts
por: Park, Jin Hee, et al.
Publicado: (2012)

PTEN downregulation induces apoptosis and cell cycle arrest in uterine cervical cancer cells
por: Shin, Jin Woo, et al.
Publicado: (2021)

Effect of aging on the formation and growth of colonic epithelial organoids by changes in cell cycle arrest through TGF-β-Smad3 signaling
por: Jo, Min Kyoung, et al.
Publicado: (2023)

Nurr1 expression is modified by inflammation in microglia
por: Lallier, Scott W., et al.
Publicado: (2016)

Cell Sources, Liver Support Systems and Liver Tissue Engineering: Alternatives to Liver Transplantation
por: Lee, Soo Young, et al.
Publicado: (2015)

The molecular architecture of cell cycle arrest
por: Stallaert, Wayne, et al.
Publicado: (2022)

The Orphan Nuclear Receptor Nurr1 Restricts the Proliferation of Hematopoietic Stem Cells
por: Sirin, Olga, et al.
Publicado: (2010)

Combined Nurr1 and Foxa2 roles in the therapy of Parkinson's disease
por: Oh, Sang-Min, et al.
Publicado: (2015)

Combined Nurr1 and Foxa2 roles in the therapy of Parkinson's disease
por: Oh, Sang‐Min, et al.
Publicado: (2016)

Resveratrol induced reactive oxygen species and endoplasmic reticulum stress-mediated apoptosis, and cell cycle arrest in the A375SM malignant melanoma cell line
por: Heo, Jae-Rim, et al.
Publicado: (2018)

PIASγ Enhanced SUMO-2 Modification of Nurr1 Activation-Function-1 Domain Limits Nurr1 Transcriptional Synergy
por: Arredondo, Cristian, et al.
Publicado: (2013)

Geranium thunbergii extract-induced G1 phase cell cycle arrest and apoptosis in gastric cancer cells
por: Lee, Hana, et al.
Publicado: (2019)

Inhibitory Effect of Synthetic Flavone Derivatives on Pan-Aurora Kinases: Induction of G2/M Cell-Cycle Arrest and Apoptosis in HCT116 Human Colon Cancer Cells
por: Shin, Soon Young, et al.
Publicado: (2018)

Molecular characterization and analysis of the porcine NURR1 gene
por: Larsen, Knud, et al.
Publicado: (2016)

NURR1 Downregulation Favors Osteoblastic Differentiation of MSCs
por: Di Benedetto, Adriana, et al.
Publicado: (2017)

Nurr1 Modulation Mediates Neuroprotective Effects of Statins
por: Willems, Sabine, et al.
Publicado: (2022)

The role of NURR1 in metabolic abnormalities of Parkinson’s disease
por: Al-Nusaif, Murad, et al.
Publicado: (2022)

Bleomycin Inhibits Proliferation via Schlafen-Mediated Cell Cycle Arrest in Mouse Alveolar Epithelial Cells
por: Jang, Soojin, et al.
Publicado: (2019)

Correction for Zhao et al., Integrative analysis reveals structural basis for transcription activation of Nurr1 and Nurr1-RXRα heterodimer
Publicado: (2023)

Function of cell-cycle regulators in predicting silent pituitary adenoma progression following surgical resection
por: Park, Sung Hyun, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_lruf7g62spi0k11e5uapeb4vcq