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Disease Risk and GVHD Biomarkers Can Stratify Patients For Risk of Relapse and Non-Relapse Mortality Post Hematopoietic Cell Transplant

The graft-versus-leukemia (GVL) effect after allogeneic hematopoietic cell transplant (HCT) can prevent relapse but the risk of severe graft-vs-host disease (GVHD) leads to prolonged intensive immunosuppression and possible blunting of the GVL effect. Strategies to reduce immunosuppression in order...

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Detalles Bibliográficos
Autores principales: Aziz, Mina D., Shah, Jay, Kapoor, Urvi, Dimopoulos, Christina, Anand, Sarah, Augustine, Allan, Ayuk, Francis, Chaudhry, Mohammed, Chen, Yi-Bin, Choe, Hannah K., Etra, Aaron, Gergoudis, Stephanie, Hartwell, Matthew J., Hexner, Elizabeth O., Hogan, William J., Kitko, Carrie L., Kowalyk, Steven, Kröger, Nicolaus, Merli, Pietro, Morales, George, Nakamura, Ryotaro, Ordemann, Rainer, Pulsipher, Michael A., Qayed, Muna, Reshef, Ran, Rösler, Wolf, Schechter, Tal, Schreiner, Elisabeth, Srinagesh, Hrishikesh, Wölfl, Matthias, Wudhikarn, Kitsada, Yanik, Gregory, Young, Rachel, Özbek, Umut, Ferrara, James L.M., Levine, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332389/
https://www.ncbi.nlm.nih.gov/pubmed/32020045
http://dx.doi.org/10.1038/s41375-020-0726-z