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COVID-19: Clinical aspects and therapeutics responses
COVID-19 has created havoc in the world by causing thousands of demises in a short period of time. Up till now, several attempts have been made for potential therapeutics against SARS-COV2. In this retrospective, single-center study, we extracted data from 122 COVID-19, RT-PCR confirmed patients. wh...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332461/ https://www.ncbi.nlm.nih.gov/pubmed/32788835 http://dx.doi.org/10.1016/j.jsps.2020.06.022 |
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author | Khan, Suliman Ali, Ashaq Shi, Hongwei Siddique, Rabeea Shabana Nabi, Ghulam Hu, Junjie Wang, Tiejun Dong, Men Zaman, Wajid Han, Guang |
author_facet | Khan, Suliman Ali, Ashaq Shi, Hongwei Siddique, Rabeea Shabana Nabi, Ghulam Hu, Junjie Wang, Tiejun Dong, Men Zaman, Wajid Han, Guang |
author_sort | Khan, Suliman |
collection | PubMed |
description | COVID-19 has created havoc in the world by causing thousands of demises in a short period of time. Up till now, several attempts have been made for potential therapeutics against SARS-COV2. In this retrospective, single-center study, we extracted data from 122 COVID-19, RT-PCR confirmed patients. who were treated with a new treatment strategy of lianhuaqingwen with Arbidol Hydrochloride. The patients were either asymptomatic or had mild symptoms for COVID-19 disease. Of 122 patients 21 (17.21%) patients developed severe conditions of COVID-19, while total 111 (90.9%) experienced mild symptoms such as fever in 93 (76.22%) patients, cough in 23 (20.17%) and muscle pain were observed in total 8 (7%) patients. Furthermore our newly applied drugs combination (Lianhuaqingwen and Arbidol Hydrochloride) showed therapeutic effects in 5–7 days in patients with mild symptoms with 98% recovery rate. These results indicate that COVID-19 patients with mild symptoms can be treated with Lianhuaqingwen and Arbidol Hydrochloride. However, extensive clinical investigations are required to confirm the effectiveness of these drugs. |
format | Online Article Text |
id | pubmed-7332461 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-73324612020-07-06 COVID-19: Clinical aspects and therapeutics responses Khan, Suliman Ali, Ashaq Shi, Hongwei Siddique, Rabeea Shabana Nabi, Ghulam Hu, Junjie Wang, Tiejun Dong, Men Zaman, Wajid Han, Guang Saudi Pharm J Article COVID-19 has created havoc in the world by causing thousands of demises in a short period of time. Up till now, several attempts have been made for potential therapeutics against SARS-COV2. In this retrospective, single-center study, we extracted data from 122 COVID-19, RT-PCR confirmed patients. who were treated with a new treatment strategy of lianhuaqingwen with Arbidol Hydrochloride. The patients were either asymptomatic or had mild symptoms for COVID-19 disease. Of 122 patients 21 (17.21%) patients developed severe conditions of COVID-19, while total 111 (90.9%) experienced mild symptoms such as fever in 93 (76.22%) patients, cough in 23 (20.17%) and muscle pain were observed in total 8 (7%) patients. Furthermore our newly applied drugs combination (Lianhuaqingwen and Arbidol Hydrochloride) showed therapeutic effects in 5–7 days in patients with mild symptoms with 98% recovery rate. These results indicate that COVID-19 patients with mild symptoms can be treated with Lianhuaqingwen and Arbidol Hydrochloride. However, extensive clinical investigations are required to confirm the effectiveness of these drugs. Elsevier 2020-08 2020-07-03 /pmc/articles/PMC7332461/ /pubmed/32788835 http://dx.doi.org/10.1016/j.jsps.2020.06.022 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Khan, Suliman Ali, Ashaq Shi, Hongwei Siddique, Rabeea Shabana Nabi, Ghulam Hu, Junjie Wang, Tiejun Dong, Men Zaman, Wajid Han, Guang COVID-19: Clinical aspects and therapeutics responses |
title | COVID-19: Clinical aspects and therapeutics responses |
title_full | COVID-19: Clinical aspects and therapeutics responses |
title_fullStr | COVID-19: Clinical aspects and therapeutics responses |
title_full_unstemmed | COVID-19: Clinical aspects and therapeutics responses |
title_short | COVID-19: Clinical aspects and therapeutics responses |
title_sort | covid-19: clinical aspects and therapeutics responses |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332461/ https://www.ncbi.nlm.nih.gov/pubmed/32788835 http://dx.doi.org/10.1016/j.jsps.2020.06.022 |
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