A reformulation of pLSA for uncertainty estimation and hypothesis testing in bio-imaging

MOTIVATION: Probabilistic latent semantic analysis (pLSA) is commonly applied to describe mass spectra (MS) images. However, the method does not provide certain outputs necessary for the quantitative scientific interpretation of data. In particular, it lacks assessment of statistical uncertainty and...

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Detalles Bibliográficos
Autores principales: Tar, P D, Thacker, N A, Deepaisarn, S, O’Connor, J P B, McMahon, A W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332574/
https://www.ncbi.nlm.nih.gov/pubmed/32348460
http://dx.doi.org/10.1093/bioinformatics/btaa270

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