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The First Known Case of Liver Abscess Caused by Aggregatibacter aphrophilus in Japan

A 48-year-old man presented with a sustained fever. Abdominal computed tomography revealed multilocular liver abscesses. He underwent percutaneous needle aspiration, yielding straw-colored pus. Gram staining revealed Gram-negative coccobacilli. The organism grew only on chocolate II agar in a 7% car...

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Detalles Bibliográficos
Autores principales: Okumura, Taiki, Soya, Keisuke, Hihara, Yu, Muraoka, Shinji, Nishimura, Yoshihiro, Inoue, Katsuaki, Maruyama, Atsushi, Matsumoto, Go
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332619/
https://www.ncbi.nlm.nih.gov/pubmed/32161220
http://dx.doi.org/10.2169/internalmedicine.4220-19
Descripción
Sumario:A 48-year-old man presented with a sustained fever. Abdominal computed tomography revealed multilocular liver abscesses. He underwent percutaneous needle aspiration, yielding straw-colored pus. Gram staining revealed Gram-negative coccobacilli. The organism grew only on chocolate II agar in a 7% carbon dioxide atmosphere. Identification of Aggregatibacter aphrophilus was confirmed using mass spectrometry and 16S rRNA gene sequencing. He was successfully treated with antibiotics. Liver abscess caused by A. aphrophilus is extremely rare. We herein report the first such case in Japan. Even fastidious organisms, such as A. aphrophilus, should be correctly identified using mass spectrometry or 16S rRNA gene sequencing for adequate treatment.