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Arsenic trioxide induces regulatory functions of plasmacytoid dendritic cells through interferon-α inhibition
Arsenic trioxide (As(2)O(3)) is recently found to have therapeutic potential in systemic sclerosis (SSc), a life-threatening multi-system fibrosing autoimmune disease with type I interferon (IFN-I) signature. Chronically activated plasmacytoid dendritic cells (pDCs) are responsible for IFN-I secreti...
Autores principales: | Ye, Yishan, Ricard, Laure, Siblany, Lama, Stocker, Nicolas, De Vassoigne, Frédéric, Brissot, Eolia, Lamarthée, Baptiste, Mekinian, Arsène, Mohty, Mohamad, Gaugler, Béatrice, Malard, Florent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332672/ https://www.ncbi.nlm.nih.gov/pubmed/32642412 http://dx.doi.org/10.1016/j.apsb.2020.01.016 |
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