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Slit1 Protein Regulates SVZ-Derived Precursor Mobilization in the Adult Demyelinated CNS

Slit1 is a secreted axon guidance molecule, also involved in adult neurogenesis. In physiological conditions, Slit1 loss promotes ectopic dispersal of SVZ-derived neural precursors (SVZ-NPCs) into periventricular structures such as the corpus callosum. Demyelination of the corpus callosum triggers S...

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Detalles Bibliográficos
Autores principales: Deboux, C., Spigoni, G., Caillava, C., Garcia-Diaz, B., Ypsilanti, A., Sarrazin, N., Bachelin, C., Chédotal, A., Baron-Van Evercooren, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332780/
https://www.ncbi.nlm.nih.gov/pubmed/32670024
http://dx.doi.org/10.3389/fncel.2020.00168

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