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LGR5 controls extracellular matrix production by stem cells in the developing intestine

The Lgr5 receptor is a marker of intestinal stem cells (ISCs) that regulates Wnt/b‐catenin signaling. In this study, phenotype analysis of knockin/knockout Lgr5‐eGFP‐IRES‐Cre and Lgr5‐DTReGFP embryos reveals that Lgr5 deficiency during Wnt‐mediated cytodifferentiation results in amplification of ISC...

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Detalles Bibliográficos
Autores principales:	Fernandez Vallone, Valeria, Leprovots, Morgane, Ribatallada‐Soriano, Didac, Gerbier, Romain, Lefort, Anne, Libert, Frédérick, Vassart, Gilbert, Garcia, Marie‐Isabelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332981/ https://www.ncbi.nlm.nih.gov/pubmed/32468660 http://dx.doi.org/10.15252/embr.201949224

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