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Antibody RING-Mediated Destruction of Endogenous Proteins

To understand gene function, the encoding DNA or mRNA transcript can be manipulated and the consequences observed. However, these approaches do not have a direct effect on the protein product of the gene, which is either permanently abrogated or depleted at a rate defined by the half-life of the pro...

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Detalles Bibliográficos
Autores principales: Ibrahim, Adel F.M., Shen, Linnan, Tatham, Michael H., Dickerson, David, Prescott, Alan R., Abidi, Naima, Xirodimas, Dimitris P., Hay, Ronald T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332993/
https://www.ncbi.nlm.nih.gov/pubmed/32454028
http://dx.doi.org/10.1016/j.molcel.2020.04.032

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