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Antibody RING-Mediated Destruction of Endogenous Proteins
To understand gene function, the encoding DNA or mRNA transcript can be manipulated and the consequences observed. However, these approaches do not have a direct effect on the protein product of the gene, which is either permanently abrogated or depleted at a rate defined by the half-life of the pro...
Autores principales: | Ibrahim, Adel F.M., Shen, Linnan, Tatham, Michael H., Dickerson, David, Prescott, Alan R., Abidi, Naima, Xirodimas, Dimitris P., Hay, Ronald T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332993/ https://www.ncbi.nlm.nih.gov/pubmed/32454028 http://dx.doi.org/10.1016/j.molcel.2020.04.032 |
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