Cargando…

Rectal cancer patients with downstaging after neoadjuvant chemoradiotherapy and radical resection do not benefit from adjuvant chemotherapy

BACKGROUND: Whether adjuvant chemotherapy is beneficial for rectal cancer patients who respond well to neoadjuvant chemoradiotherapy (NCRT) and undergo radical resection is controversial. This study aimed to assess the effect of adjuvant chemotherapy on the oncological outcomes of ypT0-2N0 rectal ca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Hang, Huang, Ya, Sun, Ge, Zheng, Kuo, Lou, Zheng, Gao, Xian-Hua, Hao, Li-Qiang, Liu, Lian-Jie, Meng, Rong-Gui, Zhang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333111/ https://www.ncbi.nlm.nih.gov/pubmed/32647668 http://dx.doi.org/10.21037/atm-20-1278

Ejemplares similares

Factors influencing downstaging after neoadjuvant long-course chemoradiotherapy in rectal carcinoma
por: Kohl, Valerie K. B., et al.
Publicado: (2022)

Adjuvant therapy in patients with rectal adenocarcinoma treated with neoadjuvant chemoradiotherapy and radical resection in pathological stages I–III
por: Lino-Silva, Leonardo S., et al.
Publicado: (2020)

T‐stage downstaging of locally advanced rectal cancer after neoadjuvant chemoradiotherapy is not associated with reduced recurrence after adjusting for tumour characteristics
por: Hayes, Ian P., et al.
Publicado: (2022)

Efficacy of preoperative chemoradiotherapy in downstaging rectal cancer and its impact on the long-term outcome
por: Manur, Janaki Gururajachar, et al.
Publicado: (2019)

Association between adjuvant chemotherapy and survival in patients with rectal cancer and pathological complete response after neoadjuvant chemoradiotherapy and resection
por: He, Fang, et al.
Publicado: (2020)

Benefit of Adjuvant Chemoradiotherapy in Resected Gallbladder Carcinoma
por: Kim, Tae Hyun, et al.
Publicado: (2019)

Optimize the dose of oxaliplatin for locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy followed by radical surgery and adjuvant chemotherapy
por: Chang, Hui, et al.
Publicado: (2020)

Successful Downstaging of High Rectal and Recto-Sigmoid Cancer by Neo-Adjuvant Chemo-Radiotherapy
por: O’Neill, Brian, et al.
Publicado: (2008)

Meta-analysis of oxaliplatin-based versus fluorouracil-based neoadjuvant chemoradiotherapy and adjuvant chemotherapy for locally advanced rectal cancer
por: Fu, Xing-Li, et al.
Publicado: (2017)

Retrospective research of neoadjuvant therapy on tumor-downstaging, post-operative complications, and prognosis in locally advanced rectal cancer
por: Li, Wen-Chang, et al.
Publicado: (2021)

Predictive value of carcinoembryonic antigen and carbohydrate antigen 19-9 related to downstaging to stage 0–I after neoadjuvant chemoradiotherapy in locally advanced rectal cancer
por: Song, Jianyuan, et al.
Publicado: (2018)

Beneficiaries of radical surgery among clinical complete responders to neoadjuvant chemoradiotherapy in rectal cancer
por: Zhang, Shu, et al.
Publicado: (2021)

Adjuvant chemoradiotherapy instead of revision radical resection after local excision for high-risk early rectal cancer
por: Jeong, Jae-Uk, et al.
Publicado: (2016)

Measurement of distal intramural spread and the optimal distal resection by naked eyes after neoadjuvant radiation for rectal cancers
por: Sun, Ge, et al.
Publicado: (2022)

Outcomes of neoadjuvant chemoradiotherapy followed by radical resection for T4 colorectal cancer
por: Huang, Chun-Ming, et al.
Publicado: (2020)

Prognosis of rectal cancer patients improves with downstaging by intensified neoadjuvant radiochemotherapy - a matched pair analysis
por: Schiffmann, Leif, et al.
Publicado: (2013)

Significance of Neoadjuvant Downstaging in Carcinoma of Esophagus and Gastroesophageal Junction
por: Kamarajah, S. K., et al.
Publicado: (2020)

Reply: Adjuvant chemoradiotherapy is no alternative to intensified neoadjuvant chemoradiotherapy for local and systemic control in patients with locally advanced rectal cancer
por: Klautke, G, et al.
Publicado: (2006)

Is adjuvant chemotherapy necessary for patients with ypT0–2N0 rectal cancer treated with neoadjuvant chemoradiotherapy and curative surgery?
por: Lu, Zhao, et al.
Publicado: (2018)

Local resection versus radical resection after neoadjuvant chemoradiotherapy for patients with locally advanced rectal cancer: a propensity-score matched cohort analysis
por: Wang, Guancong, et al.
Publicado: (2023)

Downstaging of a Rectal Gastrointestinal Stromal Tumor by Neoadjuvant Imatinib Therapy Allowing for a Conservative Surgical Approach
por: dos Santos Fernandes, Gustavo, et al.
Publicado: (2009)

The watch-and-wait strategy versus radical resection for rectal cancer patients with a good response (≤ycT2) after neoadjuvant chemoradiotherapy
por: Lee, Chungyeop, et al.
Publicado: (2022)

Selection of Adjuvant Treatment Without Neoadjuvant Chemoradiotherapy for Patients With Rectal Cancer: Room for Further Investigation
por: Park, In Ja
Publicado: (2018)

Predictive Factors for Pathologic Complete Response Following Neoadjuvant Chemoradiotherapy for Rectal Cancer
por: Zhang, Qi, et al.
Publicado: (2021)

Restaging rectal cancer following neoadjuvant chemoradiotherapy
por: Cuicchi, Dajana, et al.
Publicado: (2023)

Adjuvant chemoradiotherapy for patients with pathologic node-positive esophageal cancer following radical resection is associated with improved survival
por: Zheng, Bin, et al.
Publicado: (2020)

Molecular downstaging: a new paradigm for neoadjuvant endocrine therapy
por: Ferraro, Emanuela, et al.
Publicado: (2020)

Adding Adjuvants to Fluoropyrimidine-based Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer: An Option Worthy of Serious Consideration
por: Wu, Fengpeng, et al.
Publicado: (2021)

Neoadjuvant chemoradiotherapy or radiotherapy in patients aged 75 years or older with locally advanced rectal cancer
por: Liu, Xiaoliang, et al.
Publicado: (2020)

Impact of interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer patients
por: Mei, Shi-Wen, et al.
Publicado: (2020)

Extended distal pancreatectomy with thoracic wall resection after neoadjuvant FOLFIRINOX: Is there a limit of resection for pancreatic cancer after downstaging?
por: Giuliani, Tommaso, et al.
Publicado: (2020)

Benefit of adjuvant chemoradiotherapy in patients with pathological stage III gastric cancer
por: Ma, Gui-Fen, et al.
Publicado: (2019)

Loop ostomy following laparoscopic low anterior resection for rectal cancer after neoadjuvant chemoradiotherapy
por: Wu, Xin, et al.
Publicado: (2018)

Nomogram Predicting Overall Survival of Resected Locally Advanced Rectal Cancer Patients with Neoadjuvant Chemoradiotherapy
por: Song, Jianyuan, et al.
Publicado: (2020)

Clinical benefit of adding oxaliplatin to standard neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a meta-analysis: Oxaliplatin in neoadjuvant treatment for rectal cancer
por: De Felice, Francesca, et al.
Publicado: (2017)

Use of patient‐derived tumor organoid platform to predict the benefit of postoperative adjuvant chemotherapy for poor responders to neoadjuvant chemoradiotherapy in locally advanced rectal cancer
por: Xue, Weisong, et al.
Publicado: (2023)

Liver Resection after Downstaging Hepatocellular Carcinoma with Sorafenib
por: Barbier, L., et al.
Publicado: (2011)

Meta-analysis of neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for locally advanced rectal cancer
por: Lin, Huaqin, et al.
Publicado: (2021)

Adjuvant chemotherapy for locally advanced rectal cancer in elderly patients after neoadjuvant chemoradiotherapy and surgery: Toxicity and survival outcomes
por: Sun, Quanquan, et al.
Publicado: (2020)

Selective lateral lymph node dissection after neoadjuvant chemoradiotherapy in rectal cancer
por: Chen, Jia-Nan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_di5t0nsuvoh3c4r8npqmelumhe