Diabetes induces hepatocyte pyroptosis by promoting oxidative stress-mediated NLRP3 inflammasome activation during liver ischaemia and reperfusion injury

BACKGROUND: Although diabetes mellitus has been reported to aggravate liver ischaemia and reperfusion (IR) injury, the basic mechanism remains largely unknown. The object of the present study was to determine the role of oxidative stress and hepatocellular pyroptosis in liver IR injury in diabetic m...

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Detalles Bibliográficos
Autores principales: Shi, Chengyu, Wang, Qi, Rao, Zhuqing, Shi, Yong, Wei, Song, Wang, Hao, Lu, Xu, Wang, Ping, Lu, Ling, Zhou, Haoming, Cheng, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333130/
https://www.ncbi.nlm.nih.gov/pubmed/32647664
http://dx.doi.org/10.21037/atm-20-1839

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