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DiNeR: a Differential graphical model for analysis of co-regulation Network Rewiring
BACKGROUND: During transcription, numerous transcription factors (TFs) bind to targets in a highly coordinated manner to control the gene expression. Alterations in groups of TF-binding profiles (i.e. “co-binding changes”) can affect the co-regulating associations between TFs (i.e. “rewiring the co-...
Autores principales: | Zhang, Jing, Liu, Jason, Lee, Donghoon, Lou, Shaoke, Chen, Zhanlin, Gürsoy, Gamze, Gerstein, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333332/ https://www.ncbi.nlm.nih.gov/pubmed/32615918 http://dx.doi.org/10.1186/s12859-020-03605-3 |
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