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nanoDSF: In vitro Label-Free Method to Monitor Picornavirus Uncoating and Test Compounds Affecting Particle Stability
Thermal shift assays measure the stability of macromolecules and macromolecular assemblies as a function of temperature. The Particle Stability Thermal Release Assay (PaSTRy) of picornaviruses is based on probes becoming strongly fluorescent upon binding to hydrophobic patches of the protein capsid...
Autores principales: | Real-Hohn, Antonio, Groznica, Martin, Löffler, Nadine, Blaas, Dieter, Kowalski, Heinrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333345/ https://www.ncbi.nlm.nih.gov/pubmed/32676065 http://dx.doi.org/10.3389/fmicb.2020.01442 |
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