Cargando…
LymphoAtlas: a dynamic and integrated phosphoproteomic resource of TCR signaling in primary T cells reveals ITSN2 as a regulator of effector functions
T‐cell receptor (TCR) ligation‐mediated protein phosphorylation regulates the activation, cellular responses, and fates of T cells. Here, we used time‐resolved high‐resolution phosphoproteomics to identify, quantify, and characterize the phosphorylation dynamics of thousands of phosphorylation sites...
Autores principales: | Locard‐Paulet, Marie, Voisinne, Guillaume, Froment, Carine, Goncalves Menoita, Marisa, Ounoughene, Youcef, Girard, Laura, Gregoire, Claude, Mori, Daiki, Martinez, Manuel, Luche, Hervé, Garin, Jerôme, Malissen, Marie, Burlet‐Schiltz, Odile, Malissen, Bernard, Gonzalez de Peredo, Anne, Roncagalli, Romain |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333348/ https://www.ncbi.nlm.nih.gov/pubmed/32618424 http://dx.doi.org/10.15252/msb.20209524 |
Ejemplares similares
-
Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics
por: Voisinne, Guillaume, et al.
Publicado: (2019) -
Kinetic proofreading through the multi-step activation of the ZAP70 kinase underlies early T cell ligand discrimination
por: Voisinne, Guillaume, et al.
Publicado: (2022) -
Co‐recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR‐induced ubiquitylation
por: Voisinne, Guillaume, et al.
Publicado: (2016) -
Systems-level conservation of the proximal TCR signaling network of mice and humans
por: Nicolas, Philippe, et al.
Publicado: (2022) -
Opposing regulatory functions of the TIM3 (HAVCR2) signalosome in primary effector T cells as revealed by quantitative interactomics
por: Zhai, Yunhao, et al.
Publicado: (2020)