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A multidimensional systems biology analysis of cellular senescence in aging and disease

BACKGROUND: Cellular senescence, a permanent state of replicative arrest in otherwise proliferating cells, is a hallmark of aging and has been linked to aging-related diseases. Many genes play a role in cellular senescence, yet a comprehensive understanding of its pathways is still lacking. RESULTS:...

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Detalles Bibliográficos
Autores principales:	Avelar, Roberto A., Ortega, Javier Gómez, Tacutu, Robi, Tyler, Eleanor J., Bennett, Dominic, Binetti, Paolo, Budovsky, Arie, Chatsirisupachai, Kasit, Johnson, Emily, Murray, Alex, Shields, Samuel, Tejada-Martinez, Daniela, Thornton, Daniel, Fraifeld, Vadim E., Bishop, Cleo L., de Magalhães, João Pedro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333371/ https://www.ncbi.nlm.nih.gov/pubmed/32264951 http://dx.doi.org/10.1186/s13059-020-01990-9

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