Single-cell ATAC-seq signal extraction and enhancement with SCATE

Single-cell sequencing assay for transposase-accessible chromatin (scATAC-seq) is the state-of-the-art technology for analyzing genome-wide regulatory landscapes in single cells. Single-cell ATAC-seq data are sparse and noisy, and analyzing such data is challenging. Existing computational methods ca...

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Detalles Bibliográficos
Autores principales: Ji, Zhicheng, Zhou, Weiqiang, Hou, Wenpin, Ji, Hongkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333383/
https://www.ncbi.nlm.nih.gov/pubmed/32620137
http://dx.doi.org/10.1186/s13059-020-02075-3

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