Methotrexate impaired in-vivo matured mouse oocyte quality and the possible mechanisms

BACKGROUND: Methotrexate (MTX) is an antifolate agent which is widely used in clinic for treating malignancies, rheumatoid arthritis and ectopic pregnancy. As reported, MTX has side effects on gastrointestinal system, nervous system and reproductive system, while its potential damages on oocyte qual...

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Detalles Bibliográficos
Autores principales: Tian, Ning, Lv, Dan-yu, Yu, Ji, Ma, Wan-yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333412/
https://www.ncbi.nlm.nih.gov/pubmed/32620073
http://dx.doi.org/10.1186/s12860-020-00298-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333412/
https://www.ncbi.nlm.nih.gov/pubmed/32620073
http://dx.doi.org/10.1186/s12860-020-00298-7

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