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hUMSC transplantation restores ovarian function in POI rats by inhibiting autophagy of theca-interstitial cells via the AMPK/mTOR signaling pathway

BACKGROUND: Previous studies of primary ovarian insufficiency (POI) have focused on granulosa cells (GCs) and ignored the role of theca-interstitial cells (TICs). This study aims to explore the mechanism of the protective effects of human umbilical cord-derived mesenchymal stem cells (hUMSCs) on ova...

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Detalles Bibliográficos
Autores principales:	Lu, Xueyan, Bao, Hongchu, Cui, Linlu, Zhu, Wenqian, Zhang, Lianshuang, Xu, Zheng, Man, Xuejing, Chu, Yongli, Fu, Qiang, Zhang, Hongqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333437/ https://www.ncbi.nlm.nih.gov/pubmed/32620136 http://dx.doi.org/10.1186/s13287-020-01784-7

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