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NSD3S stabilizes MYC through hindering its interaction with FBXW7
The MYC transcription factor plays a key role in cell growth control. Enhanced MYC protein stability has been found to promote tumorigenesis. Thus, understanding how MYC stability is controlled may have significant implications for revealing MYC-driven growth regulatory mechanisms in physiological a...
Autores principales: | Gonzalez-Pecchi, Valentina, Kwan, Albert K, Doyle, Sean, Ivanov, Andrey A, Du, Yuhong, Fu, Haian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333476/ https://www.ncbi.nlm.nih.gov/pubmed/31638140 http://dx.doi.org/10.1093/jmcb/mjz098 |
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