Loss of mismatch repair signaling impairs the WNT–bone morphogenetic protein crosstalk and the colonic homeostasis

The fine balance between proliferation, differentiation, and apoptosis in the colonic epithelium is tightly controlled by the interplay between WNT, Notch, and bone morphogenetic protein (BMP) signaling. How these complex networks coordinate the colonic homeostasis, especially if cancer predisposing...

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Detalles Bibliográficos
Autores principales: Nørgaard, Katrine, Müller, Carolin, Christensen, Nadja, Chiloeches, María L, Madsen, Cesilie L, Nielsen, Sabine S, Thingholm, Tine E, Belcheva, Antoaneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333479/
https://www.ncbi.nlm.nih.gov/pubmed/31065691
http://dx.doi.org/10.1093/jmcb/mjz031

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