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Type 5 phosphodiesterase (PDE5) and the vascular tree: From embryogenesis to aging and disease
Vascular tree development depends on the timely differentiation of endothelial and vascular smooth muscle cells. These latter are key players in the formation of the vascular scaffold that offers resistance to the blood flow. This review aims at providing an overview on the role of PDE5, the cGMP-sp...
Autores principales: | Cesarini, Valeriana, Guida, Eugenia, Campolo, Federica, Crescioli, Clara, Di Baldassarre, Angela, Pisano, Calogera, Balistreri, Carmela Rita, Ruvolo, Giovanni, Jannini, Emmanuele A., Dolci, Susanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333613/ https://www.ncbi.nlm.nih.gov/pubmed/32628940 http://dx.doi.org/10.1016/j.mad.2020.111311 |
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