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Macrophage Sphingosine 1-Phosphate Receptor 2 Blockade Attenuates Liver Inflammation and Fibrogenesis Triggered by NLRP3 Inflammasome

NLR family pyrin domain containing 3 (NLRP3) inflammasome accompanies chronic liver injury and is a critical mediator of inflammation-driven liver fibrosis. Sphingosine 1-phosphate (S1P)/S1P Receptor (S1PR) signaling participates in liver fibrogenesis by affecting bone marrow (BM)-derived monocytes/...

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Detalles Bibliográficos
Autores principales:	Hou, Lei, Yang, Le, Chang, Na, Zhao, Xinhao, Zhou, Xuan, Dong, Chengbin, Liu, Fuquan, Yang, Lin, Li, Liying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333785/ https://www.ncbi.nlm.nih.gov/pubmed/32695095 http://dx.doi.org/10.3389/fimmu.2020.01149

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