Assessment of associations between clinical and immune microenvironmental factors and tumor mutation burden in resected nonsmall cell lung cancer by applying machine learning to whole‐slide images

BACKGROUND: It is unclear whether clinical factors and immune microenvironment (IME) factors are associated with tumor mutation burden (TMB) in patients with nonsmall cell lung cancer (NSCLC). MATERIALS AND METHODS: We assessed TMB in surgical tumor specimens by performing whole exome sequencing. IM...

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Detalles Bibliográficos
Autores principales: Ono, Akira, Terada, Yukihiro, Kawata, Takuya, Serizawa, Masakuni, Isaka, Mitsuhiro, Kawabata, Takanori, Imai, Toru, Mori, Keita, Muramatsu, Koji, Hayashi, Isamu, Kenmotsu, Hirotsugu, Ohshima, Keiichi, Urakami, Kenichi, Nagashima, Takeshi, Kusuhara, Masatoshi, Akiyama, Yasuto, Sugino, Takashi, Ohde, Yasuhisa, Yamaguchi, Ken, Takahashi, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cancer Prevention
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333844/
https://www.ncbi.nlm.nih.gov/pubmed/32400056
http://dx.doi.org/10.1002/cam4.3107

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