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The centromere comes into focus: from CENP-A nucleosomes to kinetochore connections with the spindle
Eukaryotic chromosome segregation relies upon specific connections from DNA to the microtubule-based spindle that forms at cell division. The chromosomal locus that directs this process is the centromere, where a structure called the kinetochore forms upon entry into mitosis. Recent crystallography...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333888/ https://www.ncbi.nlm.nih.gov/pubmed/32516549 http://dx.doi.org/10.1098/rsob.200051 |