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Three-dimensional chromatin interactions remain stable upon CAG/CTG repeat expansion

Expanded CAG/CTG repeats underlie 13 neurological disorders, including myotonic dystrophy type 1 (DM1) and Huntington’s disease (HD). Upon expansion, disease loci acquire heterochromatic characteristics, which may provoke changes to chromatin conformation and thereby affect both gene expression and...

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Detalles Bibliográficos
Autores principales:	Ruiz Buendía, Gustavo A., Leleu, Marion, Marzetta, Flavia, Vanzan, Ludovica, Tan, Jennifer Y., Ythier, Victor, Randall, Emma L., Marques, Ana C., Baubec, Tuncay, Murr, Rabih, Xenarios, Ioannis, Dion, Vincent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334000/ https://www.ncbi.nlm.nih.gov/pubmed/32656337 http://dx.doi.org/10.1126/sciadv.aaz4012

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