Community-Acquired Methicillin-Resistant Staphylococcus aureus ST59 in a Chinese Adult with Meningitis: A Case Report from China

Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are reported worldwide and are associated with serious outcomes. The majority of CA-MRSA infections are soft tissue and skin infections, and cases with meningitis caused by CA-MRSA are rare. Here, we reported a 53-ye...

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Autores principales: Chen, Fayu, Chen, Yan, Zhao, Xiaofei, Wang, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334018/
https://www.ncbi.nlm.nih.gov/pubmed/32636654
http://dx.doi.org/10.2147/IDR.S253407
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author Chen, Fayu
Chen, Yan
Zhao, Xiaofei
Wang, Jianfeng
author_facet Chen, Fayu
Chen, Yan
Zhao, Xiaofei
Wang, Jianfeng
author_sort Chen, Fayu
collection PubMed
description Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are reported worldwide and are associated with serious outcomes. The majority of CA-MRSA infections are soft tissue and skin infections, and cases with meningitis caused by CA-MRSA are rare. Here, we reported a 53-year-old male patient with meningitis due to CA-MRSA infection, as confirmed by cerebrospinal fluid examination. Whole-genome sequencing data revealed an ST59 CA-MRSA strain encoding PVL and SCCmec IV. Linezolid was administered in this case, and the patient recovered, with no signs of relapse during the one-year follow-up. We present the first case of PVL-positive ST59 CA-MRSA meningitis, with severe manifestations in China.
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spelling pubmed-73340182020-07-06 Community-Acquired Methicillin-Resistant Staphylococcus aureus ST59 in a Chinese Adult with Meningitis: A Case Report from China Chen, Fayu Chen, Yan Zhao, Xiaofei Wang, Jianfeng Infect Drug Resist Case Report Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are reported worldwide and are associated with serious outcomes. The majority of CA-MRSA infections are soft tissue and skin infections, and cases with meningitis caused by CA-MRSA are rare. Here, we reported a 53-year-old male patient with meningitis due to CA-MRSA infection, as confirmed by cerebrospinal fluid examination. Whole-genome sequencing data revealed an ST59 CA-MRSA strain encoding PVL and SCCmec IV. Linezolid was administered in this case, and the patient recovered, with no signs of relapse during the one-year follow-up. We present the first case of PVL-positive ST59 CA-MRSA meningitis, with severe manifestations in China. Dove 2020-06-29 /pmc/articles/PMC7334018/ /pubmed/32636654 http://dx.doi.org/10.2147/IDR.S253407 Text en © 2020 Chen et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Chen, Fayu
Chen, Yan
Zhao, Xiaofei
Wang, Jianfeng
Community-Acquired Methicillin-Resistant Staphylococcus aureus ST59 in a Chinese Adult with Meningitis: A Case Report from China
title Community-Acquired Methicillin-Resistant Staphylococcus aureus ST59 in a Chinese Adult with Meningitis: A Case Report from China
title_full Community-Acquired Methicillin-Resistant Staphylococcus aureus ST59 in a Chinese Adult with Meningitis: A Case Report from China
title_fullStr Community-Acquired Methicillin-Resistant Staphylococcus aureus ST59 in a Chinese Adult with Meningitis: A Case Report from China
title_full_unstemmed Community-Acquired Methicillin-Resistant Staphylococcus aureus ST59 in a Chinese Adult with Meningitis: A Case Report from China
title_short Community-Acquired Methicillin-Resistant Staphylococcus aureus ST59 in a Chinese Adult with Meningitis: A Case Report from China
title_sort community-acquired methicillin-resistant staphylococcus aureus st59 in a chinese adult with meningitis: a case report from china
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334018/
https://www.ncbi.nlm.nih.gov/pubmed/32636654
http://dx.doi.org/10.2147/IDR.S253407
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AT wangjianfeng communityacquiredmethicillinresistantstaphylococcusaureusst59inachineseadultwithmeningitisacasereportfromchina

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