Cicatricial ectropion and madarosis associated with panitumumab treatment of metastatic colorectal cancer

PURPOSE: To report a case of cicatricial ectropion and madarosis with the use of anti-epidermal growth factor receptor medication panitumumab. OBSERVATIONS: An 82-year-old man with metastatic colorectal cancer presented with cicatricial ectropion and madarosis after starting panitumumab, an anti-epi...

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Autores principales: Jin, Haoxing D., Blessing, Nathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334291/
https://www.ncbi.nlm.nih.gov/pubmed/32642599
http://dx.doi.org/10.1016/j.ajoc.2020.100810
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author Jin, Haoxing D.
Blessing, Nathan W.
author_facet Jin, Haoxing D.
Blessing, Nathan W.
author_sort Jin, Haoxing D.
collection PubMed
description PURPOSE: To report a case of cicatricial ectropion and madarosis with the use of anti-epidermal growth factor receptor medication panitumumab. OBSERVATIONS: An 82-year-old man with metastatic colorectal cancer presented with cicatricial ectropion and madarosis after starting panitumumab, an anti-epidermal growth factor receptor medication used to treat metastatic colorectal cancer. His findings resolved several weeks after discontinuation of panitumumab and treatment with lubrication and antibiotic/steroid ointment. CONCLUSION: This case demonstrates the importance to consider potential medication side effects when treating periocular conditions in patients taking anti-epidermal growth factor receptor (anti-EGFR) agents.
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spelling pubmed-73342912020-07-07 Cicatricial ectropion and madarosis associated with panitumumab treatment of metastatic colorectal cancer Jin, Haoxing D. Blessing, Nathan W. Am J Ophthalmol Case Rep Case Report PURPOSE: To report a case of cicatricial ectropion and madarosis with the use of anti-epidermal growth factor receptor medication panitumumab. OBSERVATIONS: An 82-year-old man with metastatic colorectal cancer presented with cicatricial ectropion and madarosis after starting panitumumab, an anti-epidermal growth factor receptor medication used to treat metastatic colorectal cancer. His findings resolved several weeks after discontinuation of panitumumab and treatment with lubrication and antibiotic/steroid ointment. CONCLUSION: This case demonstrates the importance to consider potential medication side effects when treating periocular conditions in patients taking anti-epidermal growth factor receptor (anti-EGFR) agents. Elsevier 2020-06-30 /pmc/articles/PMC7334291/ /pubmed/32642599 http://dx.doi.org/10.1016/j.ajoc.2020.100810 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Jin, Haoxing D.
Blessing, Nathan W.
Cicatricial ectropion and madarosis associated with panitumumab treatment of metastatic colorectal cancer
title Cicatricial ectropion and madarosis associated with panitumumab treatment of metastatic colorectal cancer
title_full Cicatricial ectropion and madarosis associated with panitumumab treatment of metastatic colorectal cancer
title_fullStr Cicatricial ectropion and madarosis associated with panitumumab treatment of metastatic colorectal cancer
title_full_unstemmed Cicatricial ectropion and madarosis associated with panitumumab treatment of metastatic colorectal cancer
title_short Cicatricial ectropion and madarosis associated with panitumumab treatment of metastatic colorectal cancer
title_sort cicatricial ectropion and madarosis associated with panitumumab treatment of metastatic colorectal cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334291/
https://www.ncbi.nlm.nih.gov/pubmed/32642599
http://dx.doi.org/10.1016/j.ajoc.2020.100810
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