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Mode of action of a formulation containing hydrazones and saponins against leishmania spp. Role in mitochondria, proteases and reinfection process

Toxicity and poor adherence to treatment that favors the generation of resistance in the Leishmania parasites highlight the need to develop better alternatives. Here, we evaluated the in vitro effectiveness of hydrazone derived from chromanes 2-(2,3-dihydro-4H-1-benzothiopyran-4-ylidene) hydrazide (...

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Detalles Bibliográficos
Autores principales: Upegui Zapata, Yulieth A., Echeverri, Fernando, Quiñones, Winston, Torres, Fernando, Nacher, Montserrat, Rivas, Luis I., Meira, Camila dos Santos, Gedamu, Lashitew, Escobar, Gustavo, Archbold, Rosendo, Vélez, Iván D., Robledo, Sara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334304/
https://www.ncbi.nlm.nih.gov/pubmed/32734890
http://dx.doi.org/10.1016/j.ijpddr.2020.06.004