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Mode of action of a formulation containing hydrazones and saponins against leishmania spp. Role in mitochondria, proteases and reinfection process
Toxicity and poor adherence to treatment that favors the generation of resistance in the Leishmania parasites highlight the need to develop better alternatives. Here, we evaluated the in vitro effectiveness of hydrazone derived from chromanes 2-(2,3-dihydro-4H-1-benzothiopyran-4-ylidene) hydrazide (...
Autores principales: | Upegui Zapata, Yulieth A., Echeverri, Fernando, Quiñones, Winston, Torres, Fernando, Nacher, Montserrat, Rivas, Luis I., Meira, Camila dos Santos, Gedamu, Lashitew, Escobar, Gustavo, Archbold, Rosendo, Vélez, Iván D., Robledo, Sara M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334304/ https://www.ncbi.nlm.nih.gov/pubmed/32734890 http://dx.doi.org/10.1016/j.ijpddr.2020.06.004 |
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