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Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses an immediate, major threat to public health across the globe. Here we report an in-depth molecular analysis to reconstruct the evolutionary origins of the enhanced pathogenicity of SARS-CoV-2 and other coronaviruses that are severe h...

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Detalles Bibliográficos
Autores principales: Gussow, Ayal B., Auslander, Noam, Faure, Guilhem, Wolf, Yuri I., Zhang, Feng, Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334499/
https://www.ncbi.nlm.nih.gov/pubmed/32522874
http://dx.doi.org/10.1073/pnas.2008176117

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