Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis

IgG antibodies cause inflammation and organ damage in autoimmune diseases such as systemic lupus erythematosus (SLE). We investigated the metabolic profile of macrophages isolated from inflamed tissues in immune complex (IC)-associated diseases, including SLE and rheumatoid arthritis, and following...

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Detalles Bibliográficos
Autores principales: Jing, Chenzhi, Castro-Dopico, Tomas, Richoz, Nathan, Tuong, Zewen K., Ferdinand, John R., Lok, Laurence S. C., Loudon, Kevin W., Banham, Gemma D., Mathews, Rebeccah J., Cader, Zaeem, Fitzpatrick, Susan, Bashant, Kathleen R., Kaplan, Mariana J., Kaser, Arthur, Johnson, Randall S., Murphy, Michael P., Siegel, Richard M., Clatworthy, Menna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334513/
https://www.ncbi.nlm.nih.gov/pubmed/32541026
http://dx.doi.org/10.1073/pnas.2000943117

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