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Supporting data on prion protein translocation mechanism revealed by pulling force studies

The Prion protein (PrP) is a highly conserved cell surface glycoprotein. To enter the secretory pathway, the PrP precursor relies on the Sec61 complex and multiple accessory factors all gathering at the membrane of the Endoplasmic reticulum (ER). PrP topogenesis results in the formation of different...

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Detalles Bibliográficos
Autores principales: Kriegler, Theresa, Lang, Sven, Notari, Luigi, Hessa, Tara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334574/
https://www.ncbi.nlm.nih.gov/pubmed/32642528
http://dx.doi.org/10.1016/j.dib.2020.105931

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